Proteinase-3 as the major autoantigen of c-ANCA is strongly expressed in lung tissue of patients with Wegener's granulomatosis

Proteinase-3 (PR-3) is a neutral serine proteinase present in azurophil granules of human polymorphonuclear leukocytes and serves as the major target antigen of antineutrophil cytoplasmic antibodies with a cytoplasmic staining pattern (c-ANCA) in Wegener's granulomatosis (WG). The WG disease ap...

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Detalles Bibliográficos
Autores principales: Brockmann, Holger, Schwarting, Andreas, Kriegsmann, Jörg, Petrow, Peter, Gaumann, Andreas, Müller, Klaus-Michael, Galle, Peter Robert, Mayet, Werner
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111026/
https://www.ncbi.nlm.nih.gov/pubmed/12010574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111026/
https://www.ncbi.nlm.nih.gov/pubmed/12010574

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