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Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes

BACKGROUND: It has become increasingly clear that β-cell failure plays a critical role in the pathogenesis of type 2 diabetes. Free-radical mediated β-cell damage has been intensively studied in type 1 diabetes, but not in human type 2 diabetes. Therefore, we studied the protein expression of the DN...

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Detalles Bibliográficos
Autores principales: Tyrberg, Björn, Anachkov, Kamen A, Dib, Sergio A, Wang-Rodriguez, Jessica, Yoon, Kun-Ho, Levine, Fred
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111186/
https://www.ncbi.nlm.nih.gov/pubmed/12003641
http://dx.doi.org/10.1186/1472-6823-2-2