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Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes
BACKGROUND: It has become increasingly clear that β-cell failure plays a critical role in the pathogenesis of type 2 diabetes. Free-radical mediated β-cell damage has been intensively studied in type 1 diabetes, but not in human type 2 diabetes. Therefore, we studied the protein expression of the DN...
Autores principales: | Tyrberg, Björn, Anachkov, Kamen A, Dib, Sergio A, Wang-Rodriguez, Jessica, Yoon, Kun-Ho, Levine, Fred |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111186/ https://www.ncbi.nlm.nih.gov/pubmed/12003641 http://dx.doi.org/10.1186/1472-6823-2-2 |
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