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Selection of novel mediators of E2F1-induced apoptosis through retroviral expression of an antisense cDNA library

The E2F1 transcription factor is an essential mediator of p53-dependent and p53-independent apoptosis as part of an anti-tumour safeguard mechanism. In this study, a functional so-called technical knockout (TKO) approach was applied to Saos-2ERE2F1 cells that conditionally activate E2F1 by the addit...

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Detalles Bibliográficos
Autores principales: Li, Z., Stanelle, J., Leurs, C., Hanenberg, H., Pützer, B. M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1129028/
https://www.ncbi.nlm.nih.gov/pubmed/15897325
http://dx.doi.org/10.1093/nar/gki581