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Selection of novel mediators of E2F1-induced apoptosis through retroviral expression of an antisense cDNA library
The E2F1 transcription factor is an essential mediator of p53-dependent and p53-independent apoptosis as part of an anti-tumour safeguard mechanism. In this study, a functional so-called technical knockout (TKO) approach was applied to Saos-2ERE2F1 cells that conditionally activate E2F1 by the addit...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1129028/ https://www.ncbi.nlm.nih.gov/pubmed/15897325 http://dx.doi.org/10.1093/nar/gki581 |