Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies

BACKGROUND: Phenotype error causes reduction in power to detect genetic association. We present a quantification of phenotype error, also known as diagnostic error, on power and sample size calculations for case-control genetic association studies between a marker locus and a disease phenotype. We c...

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Detalles Bibliográficos
Autores principales: Edwards, Brian J, Haynes, Chad, Levenstien, Mark A, Finch, Stephen J, Gordon, Derek
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1131899/
https://www.ncbi.nlm.nih.gov/pubmed/15819990
http://dx.doi.org/10.1186/1471-2156-6-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1131899/
https://www.ncbi.nlm.nih.gov/pubmed/15819990
http://dx.doi.org/10.1186/1471-2156-6-18

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