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Internal initiation of translation of the TrkB mRNA is mediated by multiple regions within the 5′ leader

Translational regulation of the dendritically localized mRNA encoding for the neurotrophin receptor TrkB has important ramifications for synaptic function. We examined whether the TrkB mRNA is translated through an internal initiation entry site (IRES). The human TrkB 5′ leaders are derived from the...

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Detalles Bibliográficos
Autores principales: Dobson, Tara, Minic, Angela, Nielsen, Kirsten, Amiott, Elizabeth, Krushel, Les
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133793/
https://www.ncbi.nlm.nih.gov/pubmed/15908588
http://dx.doi.org/10.1093/nar/gki605