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Effective generation of transgenic pigs and mice by linker based sperm-mediated gene transfer.

BACKGROUND: Transgenic animals have become valuable tools for both research and applied purposes. The current method of gene transfer, microinjection, which is widely used in transgenic mouse production, has only had limited success in producing transgenic animals of larger or higher species. Here,...

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Detalles Bibliográficos
Autores principales: Chang, Keejong, Qian, Jin, Jiang, MeiSheng, Liu, Yi-Hsin, Wu, Ming-Che, Chen, Chi-Dar, Lai, Chao-Kuen, Lo, Hsin-Lung, Hsiao, Chin-Ton, Brown, Lucy, Bolen, James, Huang, Hsiao-I, Ho, Pei-Yu, Shih, Ping Yao, Yao, Chen-Wen, Lin, Wey-Jinq, Chen, Chung-Hsi, Wu, Fang-Yi, Lin, Yi-Jen, Xu, Jing, Wang, Ken
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC113740/
https://www.ncbi.nlm.nih.gov/pubmed/11964188
http://dx.doi.org/10.1186/1472-6750-2-5