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Selective alteration of gene expression in response to natural and synthetic retinoids.

BACKGROUND: Retinoids are very potent inducers of cellular differentiation and apoptosis, and are efficient anti-tumoral agents. Synthetic retinoids are designed to restrict their toxicity and side effects, mostly by increasing their selectivity toward each isotype of retinoic acids receptors (RARα,...

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Detalles Bibliográficos
Autores principales: Brand, Céline, Ségard, Pascaline, Plouvier, Pascal, Formstecher, Pierre, Danzé, Pierre-Marie, Lefebvre, Philippe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC113761/
https://www.ncbi.nlm.nih.gov/pubmed/12019025
http://dx.doi.org/10.1186/1471-2210-2-13