Induction of apoptosis in rat peripheral blood lymphocytes by the anticancer drug CI-994 (acetyldinaline)

ABSTRACT: CI-994 (acetyldinaline) is an investigational anticancer drug currently in clinical trials. In preclinical safety studies in rats and dogs, CI-994 resulted in significant toxicity to bone marrow and lymphoid tissue. To determine if apoptosis was involved in CI-994 toxicity, peripheral bloo...

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Detalles Bibliográficos
Autores principales: Graziano, Michael J, Spoon, Teresa A, Cockrell, Erin A, Rowse, Paul E, Gonzales, Andrea J
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC113775/
https://www.ncbi.nlm.nih.gov/pubmed/12488610
http://dx.doi.org/10.1155/S1110724301000146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC113775/
https://www.ncbi.nlm.nih.gov/pubmed/12488610
http://dx.doi.org/10.1155/S1110724301000146

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