Cargando…

New NTP analogs: the synthesis of 4′-thioUTP and 4′-thioCTP and their utility for SELEX

The synthesis of the triphosphates of 4′-thiouridine and 4′-thiocytidine, 4′-thioUTP (7; thioUTP) and 4′-thioCTP (8; thioCTP), and their utility for SELEX (systematic evolution of ligands by exponential enrichment) is described. The new nucleoside triphosphate (NTP) analogs 7 and 8 were prepared fro...

Descripción completa

Detalles Bibliográficos
Autores principales: Kato, Yuka, Minakawa, Noriaki, Komatsu, Yasuo, Kamiya, Hiroyuki, Ogawa, Naoki, Harashima, Hideyoshi, Matsuda, Akira
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140078/
https://www.ncbi.nlm.nih.gov/pubmed/15914669
http://dx.doi.org/10.1093/nar/gki578