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Prevalence of quadruplexes in the human genome

Guanine-rich DNA sequences of a particular form have the ability to fold into four-stranded structures called G-quadruplexes. In this paper, we present a working rule to predict which primary sequences can form this structure, and describe a search algorithm to identify such sequences in genomic DNA...

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Detalles Bibliográficos
Autores principales: Huppert, Julian L., Balasubramanian, Shankar
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140081/
https://www.ncbi.nlm.nih.gov/pubmed/15914667
http://dx.doi.org/10.1093/nar/gki609