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Human XPC-hHR23B interacts with XPA-RPA in the recognition of triplex-directed psoralen DNA interstrand crosslinks

DNA interstrand crosslinks (ICLs) represent a severe form of damage that blocks DNA metabolic processes and can lead to cell death or carcinogenesis. The repair of DNA ICLs in mammals is not well characterized. We have reported previously that a key protein complex of nucleotide excision repair (NER...

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Detalles Bibliográficos
Autores principales: Thoma, Brian S., Wakasugi, Mitsuo, Christensen, Jesper, Reddy, Madhava C., Vasquez, Karen M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140082/
https://www.ncbi.nlm.nih.gov/pubmed/15914671
http://dx.doi.org/10.1093/nar/gki610