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An Immune Basis for Malaria Protection by the Sickle Cell Trait
BACKGROUND: Malaria resistance by the sickle cell trait (genotype HbAS) has served as the prime example of genetic selection for over half a century. Nevertheless, the mechanism of this resistance remains the subject of considerable debate. While it probably involves innate factors such as the reduc...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140945/ https://www.ncbi.nlm.nih.gov/pubmed/15916466 http://dx.doi.org/10.1371/journal.pmed.0020128 |