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An Immune Basis for Malaria Protection by the Sickle Cell Trait

BACKGROUND: Malaria resistance by the sickle cell trait (genotype HbAS) has served as the prime example of genetic selection for over half a century. Nevertheless, the mechanism of this resistance remains the subject of considerable debate. While it probably involves innate factors such as the reduc...

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Detalles Bibliográficos
Autores principales:	Williams, Thomas N, Mwangi, Tabitha W, Roberts, David J, Alexander, Neal D, Weatherall, David J, Wambua, Sammy, Kortok, Moses, Snow, Robert W, Marsh, Kevin
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140945/ https://www.ncbi.nlm.nih.gov/pubmed/15916466 http://dx.doi.org/10.1371/journal.pmed.0020128

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