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Isolation of CYP3A4 Inhibitors from the Black Cohosh (Cimicifuga racemosa)

Recent investigation on drug interaction has shown that some foods and herbal medicines increase the oral availability of a variety of CYP3A4 substrates, which is caused by the reduction of CYP3A4 in intestinal epithelium. During the course of our investigation on CYP3A4 interaction, we found that t...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Sachiko, Aburatani, Maki, Ohta, Tomihisa
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142198/
https://www.ncbi.nlm.nih.gov/pubmed/15937564
http://dx.doi.org/10.1093/ecam/neh086