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The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

The heterotrimeric G-protein alpha subunit has long been considered a bimodal, GTP-hydrolyzing switch controlling the duration of signal transduction by seven-transmembrane domain (7TM) cell-surface receptors. In 1996, we and others identified a superfamily of “regulator of G-protein signaling” (RGS...

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Detalles Bibliográficos
Autores principales: Siderovski, David P., Willard, Francis S.
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142213/
https://www.ncbi.nlm.nih.gov/pubmed/15951850