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Sequence determination of nucleic acids containing 5-methylisocytosine and isoguanine: identification and insight into polymerase replication of the non-natural nucleobases

Nucleobase analogs 5-methylisocytosine ((Me)isoC) and isoguanine (isoG) form a non-natural base pair in duplex nucleic acids with base pairing specificity orthogonal to the natural nucleobase pairs. Sequencing reactions were conducted with oligodeoxyribonucleotides (ODNs) containing d(Me)isoC and di...

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Detalles Bibliográficos
Autores principales: Ahle, J. David, Barr, Stephen, Chin, A. Michael, Battersby, Thomas R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142403/
https://www.ncbi.nlm.nih.gov/pubmed/15933210
http://dx.doi.org/10.1093/nar/gki628