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Prediction of solvent accessibility and sites of deleterious mutations from protein sequence
Residues that form the hydrophobic core of a protein are critical for its stability. A number of approaches have been developed to classify residues as buried or exposed. In order to optimize the classification, we have refined a suite of five methods over a large dataset and proposed a metamethod b...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142490/ https://www.ncbi.nlm.nih.gov/pubmed/15937195 http://dx.doi.org/10.1093/nar/gki633 |