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Direct molecular haplotyping by melting curve analysis of hybridization probes: beta 2-adrenergic receptor haplotypes as an example

Direct determination of the association of multiple genetic polymorphisms, or haplotyping, in individual samples is challenging because of chromosome diploidy. Here, we describe the ability of hybridization probes, commonly used as genotyping tools, to establish single nucleotide polymorphism (SNP)...

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Detalles Bibliográficos
Autores principales: Pont-Kingdon, Genevieve, Lyon, Elaine
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142492/
https://www.ncbi.nlm.nih.gov/pubmed/15937194
http://dx.doi.org/10.1093/nar/gni090