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A case-control study of the HER2 Ile655Val polymorphism in relation to risk of invasive breast cancer
BACKGROUND: Overexpression of the HER2 proto-oncogene in human cancer cells has been associated with a poor prognosis, and survival improves with therapy targeting the HER2 gene. Animal studies and protein modeling suggest that the Ile655Val polymorphism located in the transmembrane domain of the HE...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143556/ https://www.ncbi.nlm.nih.gov/pubmed/15987431 http://dx.doi.org/10.1186/bcr1004 |