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A case-only analysis of the interaction between N-acetyltransferase 2 haplotypes and tobacco smoke in breast cancer etiology

INTRODUCTION: N-acetyltransferase 2 is a polymorphic enzyme in humans. Women who possess homozygous polymorphic alleles have a slower rate of metabolic activation of aryl aromatic amines, one of the constituents of tobacco smoke that has been identified as carcinogenic. We hypothesized that women wi...

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Detalles Bibliográficos
Autores principales: Lash, Timothy L, Bradbury, Brian D, Wilk, Jemma B, Aschengrau, Ann
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143561/
https://www.ncbi.nlm.nih.gov/pubmed/15987434
http://dx.doi.org/10.1186/bcr1013