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Loss of G–A base pairs is insufficient for achieving a large opening of U4 snRNA K-turn motif
Upon binding to the 15.5K protein, two tandem-sheared G–A base pairs are formed in the internal loop of the kink-turn motif of U4 snRNA (Kt-U4). We have reported that the folding of Kt-U4 is assisted by protein binding. Unstable interactions that contribute to a large opening of the free RNA (‘k–e m...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1150281/ https://www.ncbi.nlm.nih.gov/pubmed/15956103 http://dx.doi.org/10.1093/nar/gki664 |