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Triplex-induced recombination and repair in the pyrimidine motif

Triplex-forming oligonucleotides (TFOs) bind DNA in a sequence-specific manner at polypurine/polypyrimidine sites and mediate targeted genome modification. Triplexes are formed by either pyrimidine TFOs, which bind parallel to the purine strand of the duplex (pyrimidine, parallel motif), or purine T...

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Detalles Bibliográficos
Autores principales: Kalish, Jennifer M., Seidman, Michael M., Weeks, Daniel L., Glazer, Peter M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1151591/
https://www.ncbi.nlm.nih.gov/pubmed/15961731
http://dx.doi.org/10.1093/nar/gki659