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Empirical characterization of the expression ratio noise structure in high-density oligonucleotide arrays

BACKGROUND: High-density oligonucleotide arrays (HDONAs) are a powerful tool for assessing differential mRNA expression levels. To establish the statistical significance of an observed change in expression, one must take into account the noise introduced by the enzymatic and hybridization steps, cal...

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Detalles Bibliográficos
Autores principales: Naef, Felix, Hacker, Coleen R, Patil, Nila, Magnasco, Marcelo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC115253/
https://www.ncbi.nlm.nih.gov/pubmed/11983059