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A deoxyribozyme that synthesizes 2′,5′-branched RNA with any branch-site nucleotide
RNA molecules with internal 2′,5′-branches are intermediates in RNA splicing, and branched RNAs have recently been proposed as retrotransposition intermediates. A broadly applicable in vitro synthetic route to branched RNA that does not require self-splicing introns or spliceosomes would substantial...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1153712/ https://www.ncbi.nlm.nih.gov/pubmed/15967808 http://dx.doi.org/10.1093/nar/gki656 |