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Use of SNPs to determine the breakpoints of complex deficiencies, facilitating gene mapping in Caenorhabditis elegans

BACKGROUND: Genetic deletions or deficiencies have been used for gene mapping and discovery in various organisms, ranging from the nematode Caenorhabditis elegans all the way to humans. One problem with large deletions is the determination of the location of their breakpoints. This is exacerbated in...

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Detalles Bibliográficos
Autores principales: Kadandale, Pavan, Geldziler, Brian, Hoffmann, Melissa, Singson, Andrew
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156886/
https://www.ncbi.nlm.nih.gov/pubmed/15918911
http://dx.doi.org/10.1186/1471-2156-6-28