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Use of SNPs to determine the breakpoints of complex deficiencies, facilitating gene mapping in Caenorhabditis elegans
BACKGROUND: Genetic deletions or deficiencies have been used for gene mapping and discovery in various organisms, ranging from the nematode Caenorhabditis elegans all the way to humans. One problem with large deletions is the determination of the location of their breakpoints. This is exacerbated in...
Autores principales: | Kadandale, Pavan, Geldziler, Brian, Hoffmann, Melissa, Singson, Andrew |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156886/ https://www.ncbi.nlm.nih.gov/pubmed/15918911 http://dx.doi.org/10.1186/1471-2156-6-28 |
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