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PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins

In DNA replication, the leading strand is synthesized continuously, but lagging strand synthesis requires the complex, discontinuous synthesis of Okazaki fragments, and their subsequent joining. We have used a combination of in situ extraction and dual color photobleaching to compare the dynamic pro...

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Detalles Bibliográficos
Autores principales: Sporbert, Anje, Domaing, Petra, Leonhardt, Heinrich, Cardoso, M. Cristina
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156965/
https://www.ncbi.nlm.nih.gov/pubmed/15972794
http://dx.doi.org/10.1093/nar/gki665