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PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins
In DNA replication, the leading strand is synthesized continuously, but lagging strand synthesis requires the complex, discontinuous synthesis of Okazaki fragments, and their subsequent joining. We have used a combination of in situ extraction and dual color photobleaching to compare the dynamic pro...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156965/ https://www.ncbi.nlm.nih.gov/pubmed/15972794 http://dx.doi.org/10.1093/nar/gki665 |