A T-stem slip in human mitochondrial tRNA(Leu)(CUN) governs its charging capacity

The human mitochondrial tRNA(Leu)(CUN) [hmtRNA(Leu)(CUN)] corresponds to the most abundant codon for leucine in human mitochondrial protein genes. Here, in vitro studies reveal that the U48C substitution in hmtRNA(Leu)(CUN), which corresponds to the pathological T12311C gene mutation, improved the a...

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Detalles Bibliográficos
Autores principales: Hao, Rui, Zhao, Ming-Wei, Hao, Zhan-Xi, Yao, Yong-Neng, Wang, En-Duo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1157101/
https://www.ncbi.nlm.nih.gov/pubmed/15972857
http://dx.doi.org/10.1093/nar/gki677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1157101/
https://www.ncbi.nlm.nih.gov/pubmed/15972857
http://dx.doi.org/10.1093/nar/gki677

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