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A T-stem slip in human mitochondrial tRNA(Leu)(CUN) governs its charging capacity
The human mitochondrial tRNA(Leu)(CUN) [hmtRNA(Leu)(CUN)] corresponds to the most abundant codon for leucine in human mitochondrial protein genes. Here, in vitro studies reveal that the U48C substitution in hmtRNA(Leu)(CUN), which corresponds to the pathological T12311C gene mutation, improved the a...
Autores principales: | Hao, Rui, Zhao, Ming-Wei, Hao, Zhan-Xi, Yao, Yong-Neng, Wang, En-Duo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1157101/ https://www.ncbi.nlm.nih.gov/pubmed/15972857 http://dx.doi.org/10.1093/nar/gki677 |
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