A PCR-mutagenesis strategy for rapid detection of mutations in codon 634 of the ret proto-oncogene related to MEN 2A.

BACKGROUND: Multiple endocrine neoplasias type 2A (MEN 2A) is a dominantly inherited cancer syndrome. Missence mutations in the codon encoding cysteine 634 of the ret proto-oncogene have been found in 85% of the MEN 2A families. The main tumour type always present in MEN 2A is medullar thyroid carci...

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Detalles Bibliográficos
Autores principales: Roqué, María, Pusiol, Eduardo, Perinetti, Héctor, Godoy, Clara Pott, Mayorga, Luis S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC115869/
https://www.ncbi.nlm.nih.gov/pubmed/12033991
http://dx.doi.org/10.1186/1471-2350-3-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC115869/
https://www.ncbi.nlm.nih.gov/pubmed/12033991
http://dx.doi.org/10.1186/1471-2350-3-4

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