Enhanced microarray performance using low complexity representations of the transcriptome

Low abundance mRNAs are more difficult to examine using microarrays than high abundance mRNAs due to the effect of concentration on hybridization kinetics and signal-to-noise ratios. This report describes the use of low complexity representations (LCRs) of mRNA as the targets for cDNA microarrays. I...

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Detalles Bibliográficos
Autores principales: Rondeau, Gaëlle, McClelland, Michael, Nguyen, Toan, Risques, Rosana, Wang, Yipeng, Judex, Martin, Cho, Ann H., Welsh, John
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1159120/
https://www.ncbi.nlm.nih.gov/pubmed/15987785
http://dx.doi.org/10.1093/nar/gni095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1159120/
https://www.ncbi.nlm.nih.gov/pubmed/15987785
http://dx.doi.org/10.1093/nar/gni095

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