Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference

RNA interference (RNAi)-mediated gene knockdown is a potent approach for studying gene function. We have previously reported a plasmid-based, tamoxifen-inducible gene knockdown system in cultured cells using a combined RNAi and Cre-LoxP system. Here, we validate this system in mouse and show that it...

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Detalles Bibliográficos
Autores principales: Coumoul, Xavier, Shukla, Vivek, Li, Cuiling, Wang, Rui-Hong, Deng, Chu-Xia
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1159121/
https://www.ncbi.nlm.nih.gov/pubmed/15987787
http://dx.doi.org/10.1093/nar/gni100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1159121/
https://www.ncbi.nlm.nih.gov/pubmed/15987787
http://dx.doi.org/10.1093/nar/gni100

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