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Immobilized stem–loop structured probes as conformational switches for enzymatic detection of microbial 16S rRNA
We have designed and evaluated novel DNA stem–loop structured probes for enzymatic detection of nucleic acid targets. These probes constitute a novel class of conformational switches for enzymatic activity, which in the absence of a target sterically shield an affinity label and upon hybridization o...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1159122/ https://www.ncbi.nlm.nih.gov/pubmed/15987786 http://dx.doi.org/10.1093/nar/gni101 |