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Short-term variability of biomarkers of proteinase activity in patients with emphysema associated with type Z alpha-1-antitrypsin deficiency

BACKGROUND: The burden of proteinases from inflammatory cells in the lung of subjects with type Pi ZZ of alpha-1-antitrypsin deficiency is higher than in those without the deficiency. Cross-sectional studies have shown increased levels of biomarkers of extracellular matrix degradation in vivo. Longi...

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Detalles Bibliográficos
Autores principales: Stolk, Jan, Veldhuisen, Barbara, Annovazzi, Laura, Zanone, Chiara, Versteeg, Elly M, van Kuppevelt, Toine H, Nieuwenhuizen, Willem, Iadarola, Paolo, Luisetti, Maurizio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1159172/
https://www.ncbi.nlm.nih.gov/pubmed/15927063
http://dx.doi.org/10.1186/1465-9921-6-47