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ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures
Key amino acid positions that are important for maintaining the 3D structure of a protein and/or its function(s), e.g. catalytic activity, binding to ligand, DNA or other proteins, are often under strong evolutionary constraints. Thus, the biological importance of a residue often correlates with its...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160131/ https://www.ncbi.nlm.nih.gov/pubmed/15980475 http://dx.doi.org/10.1093/nar/gki370 |