Cargando…

dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference

Off-target effects are one of the most serious problems in RNA interference (RNAi). Here, we present dsCheck (), web-based online software for estimating off-target effects caused by the long double-stranded RNA (dsRNA) used in RNAi studies. In the biochemical process of RNAi, the long dsRNA is clea...

Descripción completa

Detalles Bibliográficos
Autores principales: Naito, Yuki, Yamada, Tomoyuki, Matsumiya, Takahiro, Ui-Tei, Kumiko, Saigo, Kaoru, Morishita, Shinichi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160180/
https://www.ncbi.nlm.nih.gov/pubmed/15980542
http://dx.doi.org/10.1093/nar/gki419