GRIFFIN: a system for predicting GPCR–G-protein coupling selectivity using a support vector machine and a hidden Markov model

We describe a novel system, GRIFFIN (G-protein and Receptor Interaction Feature Finding INstrument), that predicts G-protein coupled receptor (GPCR) and G-protein coupling selectivity based on a support vector machine (SVM) and a hidden Markov model (HMM) with high sensitivity and specificity. Based...

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Detalles Bibliográficos
Autores principales: Yabuki, Yukimitsu, Muramatsu, Takahiko, Hirokawa, Takatsugu, Mukai, Hidehito, Suwa, Makiko
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160255/
https://www.ncbi.nlm.nih.gov/pubmed/15980445
http://dx.doi.org/10.1093/nar/gki495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160255/
https://www.ncbi.nlm.nih.gov/pubmed/15980445
http://dx.doi.org/10.1093/nar/gki495

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