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Binding properties and evolution of homodimers in protein–protein interaction networks

We demonstrate that protein–protein interaction networks in several eukaryotic organisms contain significantly more self-interacting proteins than expected if such homodimers randomly appeared in the course of the evolution. We also show that on average homodimers have twice as many interaction part...

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Detalles Bibliográficos
Autores principales: Ispolatov, Iaroslav, Yuryev, Anton, Mazo, Ilya, Maslov, Sergei
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160523/
https://www.ncbi.nlm.nih.gov/pubmed/15983135
http://dx.doi.org/10.1093/nar/gki678