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Control of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae

BACKGROUND: The FHIT gene is lost early in the development of many tumors. Fhit possesses intrinsic ApppA hydrolase activity though ApppA cleavage is not required for tumor suppression. Because a mutant form of Fhit that is functional in tumor suppression and defective in catalysis binds ApppA well,...

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Detalles Bibliográficos
Autores principales: Rubio-Texeira, Marta, Varnum, James M, Bieganowski, Pawel, Brenner, Charles
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC116438/
https://www.ncbi.nlm.nih.gov/pubmed/12028594
http://dx.doi.org/10.1186/1471-2199-3-7