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Determination of caspase-3 activation fails to predict chemosensitivity in primary acute myeloid leukemia blasts

BACKGROUND: Ex-vivo chemosensitivity tests that measure cell death induction may predict treatment outcome and, therefore, represent a powerful instrument for clinical decision making in cancer therapy. Such tests are, however, work intensive and, in the case of the DiSC-assay, require at least four...

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Detalles Bibliográficos
Autores principales: Staib, Peter, Tiehen, Jan, Strunk, Timo, Schinköthe, Timo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1164407/
https://www.ncbi.nlm.nih.gov/pubmed/15949045
http://dx.doi.org/10.1186/1471-2407-5-60