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Genome comparison without alignment using shortest unique substrings

BACKGROUND: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection of unique genomic regions, can be accomplished efficiently without an alignment step. Our procedure for nucleotide sequenc...

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Detalles Bibliográficos
Autores principales: Haubold, Bernhard, Pierstorff, Nora, Möller, Friedrich, Wiehe, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1166540/
https://www.ncbi.nlm.nih.gov/pubmed/15910684
http://dx.doi.org/10.1186/1471-2105-6-123