High-throughput kinase assays with protein substrates using fluorescent polymer superquenching

BACKGROUND: High-throughput screening is used by the pharmaceutical industry for identifying lead compounds that interact with targets of pharmacological interest. Because of the key role that aberrant regulation of protein phosphorylation plays in diseases such as cancer, diabetes and hypertension,...

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Detalles Bibliográficos
Autores principales: Rininsland, Frauke, Stankewicz, Casey, Weatherford, Wendy, McBranch, Duncan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1166542/
https://www.ncbi.nlm.nih.gov/pubmed/15927069
http://dx.doi.org/10.1186/1472-6750-5-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1166542/
https://www.ncbi.nlm.nih.gov/pubmed/15927069
http://dx.doi.org/10.1186/1472-6750-5-16

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