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Influence of RARα gene on MDR1 expression and P-glycoprotein function in human leukemic cells
BACKGROUND: Multidrug resistance (MDR) phenotype of malignant cells is the major problem in the chemotherapy of neoplasia. The treatment of leukemia with retinoids is aimed on the induction of leukemic cells differentiation. However the interconnections between retinoid regulated differentiation of...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1166566/ https://www.ncbi.nlm.nih.gov/pubmed/15910691 http://dx.doi.org/10.1186/1475-2867-5-15 |