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Influence of RARα gene on MDR1 expression and P-glycoprotein function in human leukemic cells

BACKGROUND: Multidrug resistance (MDR) phenotype of malignant cells is the major problem in the chemotherapy of neoplasia. The treatment of leukemia with retinoids is aimed on the induction of leukemic cells differentiation. However the interconnections between retinoid regulated differentiation of...

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Detalles Bibliográficos
Autores principales:	Stromskaya, Tatjana P, Rybalkina, Ekaterina Y, Zabotina, Tatjana N, Shishkin, Alexander A, Stavrovskaya, Alla A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1166566/ https://www.ncbi.nlm.nih.gov/pubmed/15910691 http://dx.doi.org/10.1186/1475-2867-5-15

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