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Conservation of functional domains and limited heterogeneity of HIV-1 reverse transcriptase gene following vertical transmission

BACKGROUND: The reverse transcriptase (RT) enzyme of human immunodeficiency virus type 1 (HIV-1) plays a crucial role in the life cycle of the virus by converting the single stranded RNA genome into double stranded DNA that integrates into the host chromosome. In addition, RT is also responsible for...

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Detalles Bibliográficos
Autores principales: Sundaravaradan, Vasudha, Hahn, Tobias, Ahmad, Nafees
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1166575/
https://www.ncbi.nlm.nih.gov/pubmed/15918905
http://dx.doi.org/10.1186/1742-4690-2-36