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Low solubility of unconjugated bilirubin in dimethylsulfoxide – water systems: implications for pK(a) determinations
BACKGROUND: Aqueous pK(a) values of unconjugated bilirubin are important determinants of its solubility and transport. Published pK(a) data on an analog, mesobilirubin-XIIIα, studied by (13)C-NMR in buffered solutions containing 27 and 64 vol% (C(2)H(3))(2)SO because of low aqueous solubility of mes...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC116679/ https://www.ncbi.nlm.nih.gov/pubmed/12079498 http://dx.doi.org/10.1186/1471-2091-3-17 |