Adenovirus-mediated interleukin-12 gene transfer combined with cytosine deaminase followed by 5-fluorocytosine treatment exerts potent antitumor activity in Renca tumor-bearing mice

BACKGROUND: Therapeutic gene transfer affords a clinically feasible and safe approach to cancer treatment but a more effective modality is needed to improve clinical outcomes. Combined transfer of therapeutic genes with different modes of actions may be a means to this end. Interleukin-12 (IL-12), a...

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Detalles Bibliográficos
Autores principales: Hwang, Kyung-Sun, Cho, Won-Kyung, Yoo, Jinsang, Yun, Hwan-Jung, Kim, Samyong, Im, Dong-Soo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1168891/
https://www.ncbi.nlm.nih.gov/pubmed/15910693
http://dx.doi.org/10.1186/1471-2407-5-51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1168891/
https://www.ncbi.nlm.nih.gov/pubmed/15910693
http://dx.doi.org/10.1186/1471-2407-5-51

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