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WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome

BACKGROUND: The putative tumor suppressor WWOX gene spans the common chromosomal fragile site 16D (FRA16D) at chromosome area 16q23.3-24.1. This region is a frequent target for loss of heterozygosity and chromosomal rearrangement in ovarian, breast, hepatocellular, prostate carcinomas and other neop...

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Detalles Bibliográficos
Autores principales: Nunez, María I, Rosen, Daniel G, Ludes-Meyers, John H, Abba, Martín C, Kil, Hyunsuk, Page, Robert, Klein-Szanto, Andres JP, Godwin, Andrew K, Liu, Jinsong, Mills, Gordon B, Aldaz, C Marcelo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1173095/
https://www.ncbi.nlm.nih.gov/pubmed/15982416
http://dx.doi.org/10.1186/1471-2407-5-64